Phenylalanine Increases Membrane Permeability
نویسندگان
چکیده
منابع مشابه
Eosinophil peroxidase increases membrane permeability in mammalian urinary bladder epithelium.
Eosinophil peroxidase (EPO), a cationic protein found in eosinophils, has been reported to be cytotoxic independent of its peroxidase activity. This study investigated with electrophysiological methods whether EPO is toxic to mammalian urinary bladder epithelium. Results indicate that EPO, when added to the mucosal solution, increases apical membrane conductance of urinary bladder epithelium on...
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Many protozoans and some other organisms possess contractile vacuoles (CVs), membranous organelles which help maintain cellular water/ electrolyte balance by extracting a dilute solution from the cytoplasmic colloid and expelling it from the cell (35, 37). Although the similarity of CV function in the various organisms has long been recognized, the expected similarity of morphological elements ...
متن کاملEosinophil major basic protein increases membrane permeability in mammalian urinary bladder epithelium.
The eosinophil granule protein major basic protein (MBP) is toxic to a wide variety of cell types, by a poorly understood mechanism. To determine whether the action of MBP involves an alteration in membrane permeability, we tested purified MBP on rabbit urinary bladder epithelium using transepithelial voltage-clamp techniques. Addition of nanomolar concentrations of MBP to the mucosal solution ...
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Cytoplasmic free Ca2+ (Ca2+i) was chelated to 10-20 nM in the macrophage cell line J774 either by incubation with quin2 acetoxymethyl ester in the absence of external Ca2+ (Di Virgilio, F., Lew, P.D., and Pozzan, T. (1984) Nature 310, 691-693) or by loading [ethyl-enebis(oxyethylenenitrilo)]tetraacetic acid (EGTA) into the cytoplasm via reversible permeabilization of the plasma membrane with ex...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2017
ISSN: 0002-7863,1520-5126
DOI: 10.1021/jacs.7b09219